Research Publications

NGF signaling in sensory neurons: evidence that early endosomes carry NGF retrograde signals.
Neuron. 2003 Jul 3;39(1):69-84.
Delcroix JD, Valleta JS, Wu C, Hunt SJ, Kowal AS, Mobley WC.

Traffic at the intersection of neurotrophic factor signaling and neurodegeneration.
Trends Neurosci. 2003 Feb;26(2):73-80.
Salehi A, Delcroix JD, Mobley WC

NGF signaling from clathrin-coated vesicles: evidence that signaling endosomes serve as a platform for the Ras-MAPK pathway.
Neuron. 2001 Dec 6;32(5):801-14.
Howe CL, Valletta JS, Rusnak AS, Mobley WC

Nerve growth factor signaling, neuroprotection, and neural repair.
Annu Rev Neurosci. 2001;24:1217-81. Review.
Sofroniew MV, Howe CL, Mobley WC.

Failed retrograde transport of NGF in a mouse model of Down's syndrome:
reversal of cholinergic neurodegenerative phenotypes following NGF infusion.
Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10439-44. Epub 2001 Aug 14.
Cooper JD, Salehi A, Delcroix JD, Howe CL, Belichenko PV, Chua-Couzens J,
Kilbridge JF, Carlson EJ, Epstein CJ, Mobley WC

Nerve growth factor activates persistent Rap1 signaling in endosomes.
J Neurosci. 2001 Aug 1;21(15):5406-16.
Wu C, Lai CF, Mobley WC