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Ke Zhan, Ph.D
2003 -Ph.D in Biochemistry and Molecular Biology, Indiana
University
School of Medicine
1997 - MS in Biochemistry, Chinese Academy of Sciences, Beijing,
China
1994
Research Interest:
The mechanisms of growth, function and maintenance of nervous system
are
crucial for us to understand why age-related neurodegenarative diseases
occur. The viability and maintenance of responsive neurons are basically
depend on neurotrophic factor (NTF) signals retrogradely transported
from axon terminals to neuron bodies. Recent proposed signaling endosome
hypothesis from our lab delineates
the existence and retrograde trafficking of endosomes containing the
NTF
in complex with associated signaling proteins.
My research goals are
to
define signaling pathways that employ endosomes as a platform, specific
pathways that employ endosomes to retrograde transportation, and to
discover the downstream gene expression that is regulated by NTF
signals.
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Contact me:
Lab:P256, MSLS building
725-2952
E-mail:kezhan@stanford.edu |
Recent Publication:
Phosphorylation of eukaryotic initiation factor 2 by heme-regulated
inhibitor kinase-related protein kinases in Schizosaccharomyces pombe
is
important for resistance to environmental stresses.
Zhan K, Vattem KM, Bauer BN, Dever TE, Chen JJ, Wek RC.
Mol Cell Biol 2002 Oct; 22(20):7134-46 |
