Jean-Dominique Michel Delcroix, Ph.D
Training:
2000 - PhD at the University of London
1995 - DEA in biochemistry-biophysics in Paris XI University
1993 - MSc in biochemistry and organic chemistry (Paris XI University)
1992 - BSc in biochemistry-animal physiology (Paris XI University)
Research Interest:
Axonal transport has been at the center of recent advances in the understanding
of degenerative diseases such as Alzheimer and Down’s syndrome.
Indeed, neurons project axons to target areas that are often far removed
from their cell body. Trophic communication between the target and the
cell body of neurons has been for a longtime an active subject of research.
Recent advances in molecular biology have highlighted some of the mechanisms
and the nature of this phenomenon. I focus my research on the nature
of NGF-induced endosomes carried from the synapse, at the target area,
to the cell body of neurons. The studies that I undertook are performed
in the peripheral nervous system as well as in the septum and the hippocampus
of Down’s syndrome models |
